Evaluation of skin biopsies in Al-Yarmouk teaching hospital
Keywords:
Al-Yarmouk, teaching hospital, skin biopsiesAbstract
Skin biopsy is an essential investigation for dermatologists. Histopathological findings in skin biopsies frequently assist dermatologist in the diagnosis and management of skin diseases. Objective: The study conducted to determine the types and reasons for biopsies & correlate the dermatologist diagnosis with that of histopathologist. This is a descriptive case-series two-year study of the dermato-pathological lesions encountered in the Al-Yarmouk Teaching Hospital. One year comprised the file based part and the second year follow-up part of the study. The study started in October 2008 to October 2010. Three hundred cases formed the total sample studied, 19 of them were defaulted from the study for unknown cause. A total of 281 patients completed the study out of which 102 cases comprised the file based part and 179 cases were the followed-up. Biopsy specimens were immediately placed in 10% buffered formalin. Routine sections were 3-5 µm thick. They were stained with routine Hematoxylin and eosin stains and special stains and cell Markers like Verhoeff von Gieson, Giems; CD1a, CD3, CD19, CD20, Bcl-2, S-100 protein, MART-1/MelanA, EMA when necessary. Results: The anatomic distribution pattern revealed that the head and neck were involved in the maximum number of case 107(38.07%) table 1.
Downloads
References
J.A.A. Hunter, J.A. Savin, M.V. Dahl. (eds.). Clinical dermatology.3ed ed. Blackwell Science Ltd, 2002; 37-38.
Felix Boon Bin Yap. Dermatopathology of 400 skin biopsies from Sarawak; Indian J Dermatol Venereol Leprol, 2009; 75: 518-19.
Rosalie Elenitsas, Michael E. Ming. Alguire PC, Mathes BM. Skin biopsy techniques for the internist. J Gen Intern Med 1998;13:46–54. Lask G, Moy R. Principles and techniques of cutaneous surgery. New York: McGraw-Hill; 1996 pp. 224-5.
Bart RS, Kopf AW. Techniques of biopsy of cutaneous neoplasms. J Dermatol Surg Oncol 1979; 5:980-87.
Robinson J. Fundamentals of skin biopsy. Chicago: Year-Book Medical Publishers, Inc; 1986 pp. 24-6.
Graham Colver. Outcomes of Skin Surgery. Informa Ltd, 2008; 16-17.
E. Calonje. Histopathology of the Skin: General Principles. In: Tony Burns, Stephen Breathnach, Neil Cox, and Christopher Griffiths. (eds.). Rook’s Textbook of Dermatology, 8th Edition. Wiley-Blackwell, 2010; 10.3-10.4.
Das SS, Pasricha JS. Punch grafting as a treatment for residual lesions of vitiligo. Indian J Dermatol Venereol Leprol 1992; 58:315-9.
Dalia A. Bassiouny. Punch Grafting in Vitiligo: Different Factors which Affect the Results. J Egypt Women Dermatol Soc 2010; 7: 16 – 21.
Boyd AS, Zemtsov A, Neldner KH:Puncta pruritica. Int J Dermatol 1992; 31: 370. In: William D James ;Timothy G Berger; Dirk M Elston.(eds.).Andrews' Diseases of Skin .10th ed. Saunders Elsevier,2006;56.
Crissey JT. Puncta pruritica. Int J Dermatol 1992;31:166.In: William D James;Timothy G Berger;Dirk M Elston.(eds.).Andrews' Diseases of Skin .10th ed.Saunders Elsevier,2006;56.
Khopkar U, Doshi B. Improving diagnostic yield of punch biopsies of the skin. Indian J Dermatol Venereol Leprol 2008; 74:527-31.
Julie S. Prendiville. Granuloma annulare.In: Wolff, Klaus; Goldsmith, Lowell A.; Katz, Stephen I.; Gilchrest, Barbara A.; Paller, Amy S.; Leffell, David J.(eds.). Fitzpatrick's Dermatology in General Medicine, 7th Edition. McGraw-Hill, 2008; 372.
Rosalie Elenitsas, Michael E. Ming. Biopsy Techniques.In: Elder, David E.; Elenitsas, Rosalie; Johnson, Bernett L.; Murphy, George F. (eds.). Lever's Histopathology of the Skin, 9th Edition. Lippincott Williams & Wilkins, 2005; 7-8.
Urmila Nischal, Nischal KC, Uday Khopkar. Techniques of Skin Biopsy and Practical Considerations: Journal of Cutaneous and Aesthetic Surgery 2008; 1:107-11.
Perez M, Lodha R, Nouri K. Skin biopsy techniques. In: Nouri K, Leal- Khouri S, editors. Techniques in dermatologic surgery. St. Louis: Mosby; 2003. p. 75-80.
AH Rotstein,H Rotstein. The use of Terson lens capsule forceps when performing punch biopsy of the skin.Australasian Journal of Dermatology 1997; 38:222-23.
Todd P, Garioch JJ, Humphreys S, SeywTight M, Thomson J, du Vivier AW.Evaluation of the 2 mm punch biopsy in dermatological diagnosis. Clin, Exp. Dermatol. 1996; 21: 11-13.
Stegman SJ. Tlie cutaneous punch (Commentary). Arch. Dematol 1982; 118: 943-4.
Highet AS. Champion RH. Procedures In practice: Skin biopsy. BMJ 1980; 280: 1259-60.
Lask G, Moy R. Principles and techniques of cutaneous surgery. New York: McGraw-Hill; 1996 pp. 224-5.
Bart RS, Kopf AW. Techniques of biopsy of cutaneous neoplasms. J Dermatol Surg Oncol 1979; 5:980-87.
Robinson J. Fundamentals of skin biopsy. Chicago: Year-Book Medical Publishers, Inc; 1986 pp. 24-6.
Graham Colver. Outcomes of Skin Surgery. Informa Ltd, 2008; 16-17.
E. Calonje. Histopathology of the Skin: General Principles. In: Tony Burns, Stephen Breathnach, Neil Cox, and Christopher Griffiths. (eds.). Rook’s Textbook of Dermatology, 8th Edition. Wiley-Blackwell, 2010; 10.3-10.4.
Das SS, Pasricha JS. Punch grafting as a treatment for residual lesions of vitiligo. Indian J Dermatol Venereol Leprol 1992; 58:315-9.
Dalia A. Bassiouny. Punch Grafting in Vitiligo: Different Factors which Affect the Results. J Egypt Women Dermatol Soc 2010; 7: 16 – 21.
Boyd AS, Zemtsov A, Neldner KH:Puncta pruritica. Int J Dermatol 1992; 31: 370. In: William D James ;Timothy G Berger; Dirk M Elston.(eds.).Andrews' Diseases of Skin .10th ed. Saunders Elsevier,2006;56.
Crissey JT. Puncta pruritica. Int J Dermatol 1992;31:166.In: William D James;Timothy G Berger;Dirk M Elston.(eds.).Andrews' Diseases of Skin .10th ed. Saunders Elsevier,2006;56.
Khopkar U, Doshi B. Improving diagnostic yield of punch biopsies of the skin. Indian J Dermatol Venereol Leprol 2008; 74:527-31.
Julie S. Prendiville. Granuloma annulare.In: Wolff, Klaus; Goldsmith, Lowell A.; Katz, Stephen I.; Gilchrest, Barbara A.; Paller, Amy S.; Leffell, David J.(eds.). Fitzpatrick's Dermatology in General Medicine, 7th Edition. McGraw-Hill, 2008; 372.
Rosalie Elenitsas, Michael E. Ming. Biopsy Techniques.In: Elder, David E.; Elenitsas, Rosalie; Johnson, Bernett L.; Murphy, George F. (eds.). Lever's Histopathology of the Skin, 9th Edition. Lippincott Williams & Wilkins, 2005; 7-8.
David E. Elder. Lever’s histopathology of the skin. 10th ed. Philadelphia: Lippincott Williams and Wilkins; 2009.
Koh D, Wang H, Lee J, Chia KS, Lee HP, Goh CL. Basal cell carcinoma, squamous cell carcinoma and melanoma of the skin: analysis of the Singapore Cancer Registry Data 1968-1997. Br J Dermatol. 2003; 148:1161-6.
Sellheyer K, Bergfeld WF. A retrospective biopsy study of the clinical diagnostic accuracy of common skin diseases by different specialties compared with dermatology. J Am Acad Dermatol 2005; 52:823-30.
Published
How to Cite
Issue
Section
Copyright (c) 2022 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
