Nutritional and environmental epigenetics effects on human health and diseases

Waleed Hassan Almalki; Ahmed Alshehri; Basel Saeed Almatrafi; Mohammed Abdullah Alasmari; Jawad Ali Jammal; Eyad Ahmad Alandijani

doi:10.53730/ijhs.v6nS3.6017

Authors

Waleed Hassan Almalki
Whmalki@uqu.edu.sa
Professor, Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia
Ahmed Alshehri Research Scholar, Department of Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia
Basel Saeed Almatrafi Research Scholar, Department of Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia
Mohammed Abdullah Alasmari Research Scholar, Department of Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia
Jawad Ali Jammal Research Scholar, Department of Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia
Eyad Ahmad Alandijani Research Scholar, Department of Pharmacy, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia

Keywords:

DNA methylation, epigenetics, histone modifications, gene expression, human health, diseases

Abstract

Both industrialized and developing nations see an alarming rise in adult-onset illnesses such as T2D and CVD. According to human and animal research, prenatal and early postnatal circumstances may alter a person's vulnerability to chronic diseases later in life. Epigenetic modulation of gene expression has been proposed as one of the processes through which early life environment impacts future illness risk. It is possible that our understanding of the underlying mechanisms may lead us to design new intervention strategies that can lessen the burden of sickness in later life.

Downloads

Download data is not yet available.

References

Agarwal, P., Morriseau, T. S., Kereliuk, S. M., Doucette, C. A., Wicklow, B. A., & Dolinsky, V. W. (2018). Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring. Crit Rev Clin Lab Sci, 55(2), 71-101.

Alam, R., Abdolmaleky, H. M., & Zhou, J. R. (2017). Microbiome, inflammation, epigenetic alterations, and mental diseases. Am J Med Genet B Neuropsychiatr Genet, 174(6), 651-660.

Aleksandrova, K., Romero-Mosquera, B., & Hernandez, V. (2017). Diet, Gut Microbiome and Epigenetics: Emerging Links with Inflammatory Bowel Diseases and Prospects for Management and Prevention. Nutrients, 9(9).

Andersen, B., & Millar, S. (2021). Skin epigenetics. Exp Dermatol, 30(8), 1004-1008.

Andreescu, N., Puiu, M., & Niculescu, M. (2018). Effects of Dietary Nutrients on Epigenetic Changes in Cancer. Methods Mol Biol, 1856, 121-139.

Bellanti, J. A., & Settipane, R. A. (2019). Genetics, epigenetics, and allergic disease: A gun loaded by genetics and a trigger pulled by epigenetics. Allergy Asthma Proc, 40(2), 73-75.

Berdasco, M., & Esteller, M. (2019). Clinical epigenetics: seizing opportunities for translation. Nat Rev Genet, 20(2), 109-127.

Cai, S. F., & Levine, R. L. (2019). Genetic and epigenetic determinants of AML pathogenesis. Semin Hematol, 56(2), 84-89.

Cavalli, G., & Heard, E. (2019). Advances in epigenetics link genetics to the environment and disease. Nature, 571(7766), 489-499.

Chang, C., Wu, H., & Lu, Q. (2020). The Epigenetics of Food Allergy. Adv Exp Med Biol, 1253, 141-152.

Charras, A., & Hedrich, C. M. (2019). The role of epigenetics in paediatric rheumatic disease. Curr Opin Rheumatol, 31(5), 450-463.

Chellappan, D. K., Leng, K. H., Jia, L. J., Aziz, N. A. B. A., Hoong, W. C., Qian, Y. C., . . . Chellian, J. (2018). The role of bevacizumab on tumour angiogenesis and in the management of gynaecological cancers: A review. Biomedicine & Pharmacotherapy, 102, 1127-1144.

Choi, B. Y., Han, M., Kwak, J. W., & Kim, T. H. (2021). Genetics and Epigenetics in Allergic Rhinitis. Genes (Basel), 12(12).

Coppedè, F. (2020). Epigenetics of neuromuscular disorders. Epigenomics, 12(23), 2125-2139.

Cruz-Rodriguez, N., Combita, A. L., & Zabaleta, J. (2018). Epigenetics in Hematological Malignancies. Methods Mol Biol, 1856, 87-101.

D'Agnelli, S., Arendt-Nielsen, L., Gerra, M. C., Zatorri, K., Boggiani, L., Baciarello, M., & Bignami, E. (2019). Fibromyalgia: Genetics and epigenetics insights may provide the basis for the development of diagnostic biomarkers. Mol Pain, 15, 1744806918819944.

Daskalakis, N. P., Rijal, C. M., King, C., Huckins, L. M., & Ressler, K. J. (2018). Recent Genetics and Epigenetics Approaches to PTSD. Curr Psychiatry Rep, 20(5), 30.

Devi, B., Kumar, Y., Shrivastav, B., Sharma, G. N., Gupta, G., & Dua, K. (2018). Current updates on biological and pharmacological activities of doxycycline. Panminerva Medica, 60(1), 36-39.

Dolcino, M., Friso, S., Selmi, C., & Lunardi, C. (2020). Editorial: Role of Epigenetics in Autoimmune Diseases. Front Immunol, 11, 1284.

Donahue, J. K. (2018). Editorial commentary: Epigenetics and cardiovascular disease-From concept to reality. Trends Cardiovasc Med, 28(5), 320-321.

Ermolaeva, M., Neri, F., Ori, A., & Rudolph, K. L. (2018). Cellular and epigenetic drivers of stem cell ageing. Nat Rev Mol Cell Biol, 19(9), 594-610.

Feinberg, A. (2018). The Key Role of Epigenetics in Human Disease. N Engl J Med, 379(4), 400-401.

Feng, L., & Lou, J. (2019). DNA Methylation Analysis. Methods Mol Biol, 1894, 181-227.

Fu, H., Liu, S., Bastacky, S. I., Wang, X., Tian, X. J., & Zhou, D. (2019). Diabetic kidney diseases revisited: A new perspective for a new era. Mol Metab, 30, 250-263.

Fyfe, I. (2018). Alzheimer disease: Epigenetics links ageing with Alzheimer disease. Nat Rev Neurol, 14(5), 254.

Garcia-Martinez, L., Zhang, Y., Nakata, Y., Chan, H. L., & Morey, L. (2021). Epigenetic mechanisms in breast cancer therapy and resistance. Nat Commun, 12(1), 1786.

Gautam, R. K., Sharma, S., Sharma, K., & Gupta, G. (2018). Evaluation of antiarthritic activity of butanol fraction of Punica granatum Linn. Rind extract against Freund’s complete adjuvant-induced arthritis in rats. Journal of Environmental Pathology, Toxicology and Oncology, 37(1).

Gomez, J. L. (2019). Epigenetics in Asthma. Curr Allergy Asthma Rep, 19(12), 56.

Gupta, G., Al-Malki, W. H., Kazmi, I., Thangavelu, L., Gupta, P. K., Jha, N. K., . . . Dua, K. (2021). The role of HGF/MET in liver cancer. Future medicinal chemistry, 13(21), 1829-1832.

Gupta, G., Bebawy, M., Pinto, T. d. J. A., Chellappan, D. K., Mishra, A., & Dua, K. (2018). Role of the tristetraprolin (zinc finger protein 36 homolog) gene in cancer. Critical Reviews™ in Eukaryotic Gene Expression, 28(3).

Hanahan, D. (2022). Hallmarks of Cancer: New Dimensions. Cancer Discov, 12(1), 31-46.

Harsanyi, S., Zamborsky, R., Krajciova, L., Kokavec, M., & Danisovic, L. (2020). Developmental Dysplasia of the Hip: A Review of Etiopathogenesis, Risk Factors, and Genetic Aspects. Medicina (Kaunas), 56(4).

Harvey, Z. H., Chen, Y., & Jarosz, D. F. (2018). Protein-Based Inheritance: Epigenetics beyond the Chromosome. Mol Cell, 69(2), 195-202.

Hübel, C., Marzi, S. J., Breen, G., & Bulik, C. M. (2019). Epigenetics in eating disorders: a systematic review. Mol Psychiatry, 24(6), 901-915.

Hwang, J. Y., Aromolaran, K. A., & Zukin, R. S. (2017). The emerging field of epigenetics in neurodegeneration and neuroprotection. Nat Rev Neurosci, 18(6), 347-361.

Jha, N. K., Chen, W.-C., Kumar, S., Dubey, R., Tsai, L.-W., Kar, R., . . . Gundamaraju, R. (2022). Molecular mechanisms of developmental pathways in neurological disorders: a pharmacological and therapeutic review. Open biology, 12(3), 210289.

Mathur, M., & Vyas, G. (2013). Role of nanoparticles for production of smart herbal drug-An overview. Indian Journal of Natural Products and Resources, 4, 329-338.

Muchakayala, S. K., Katari, N. K., Dongala, T., Marisetti, V. M., Vyas, G., & Vegesna, R. V. K. (2022). Eco-friendly and green chromatographic method for the simultaneous determination of chlorocresol and betamethasone dipropionate in topical formulations using Box–Behnken design. Journal of the Iranian Chemical Society, 19(4), 1397-1412.

Sachchidanand Pathak, G. G., Ritu M Gilhotra. (2021). The Role of Diazepam in Epigenetics: From the Molecular Level to Clinical Implications. Adv Mind Body Med, 35(1), 25-33.

Subramanian, V. B., Katari, N. K., Ponnam, V., Konduru, N., Dongala, T., Marisetti, V. M., & Vyas, G. (2022). Stability-indicating reversed-phase-HPLC method development and validation for sacubitril/valsartan complex in the presence of impurities and degradation products: Robustness by quality-by-design approach. Biomed Chromatogr, 36(1), e5240.

Valluri, V., Katari, N., Khatri, C., Vyas, G., Polagani, S., & Ponnam, V. (2021). Highly sensitive liquid chromatography–tandem mass spectrometry assay for the determination of azathioprine in presence of mercaptopurine and its application to a human pharmacokinetic study. Separation Science Plus, 4.

Vyas, G., Mathur, M., Patel, N. A., & Patel, R. P. (2017). Aphrodisiac Efficacy of Blepharis sindica seeds: A comparative assessment using different solvent types. Indian journal of biochemistry & biophysics, 54, 223-230.

Wadhwa, R., Paudel, K. R., Shukla, S., Shastri, M., Gupta, G., Devkota, H. P., . . . Dua, K. (2020). Epigenetic Therapy as a Potential Approach for Targeting Oxidative Stress–Induced Non-Small-Cell Lung Cancer. Handbook of Oxidative Stress in Cancer: Mechanistic Aspects, 1-16.