Therapeutic applications, nutritional composition, and their future perspectives of wild mushrooms

Gaurav Kothiyal; Keerti Singh; Ram Mahesh; Sanjeev Yadav

doi:10.53730/ijls.v9n1.15622

Authors

Gaurav Kothiyal
gauravkothiyal790@gmail.com
Government Doon Medical College Dehradun (GDMC) -248001, Uttarakhand, India
Keerti Singh Department of Microbiology, School of Paramedical & Allied Health Sciences, SGRR University Dehradun-248001, Uttarakhand, India
Ram Mahesh Soban Singh Jeena Government Institute of Medical Sciences and Research Almora, Uttarakhand, India
Sanjeev Yadav Government Doon Medical College Dehradun (GDMC) -248001, Uttarakhand, India

Keywords:

diversity, medicinal, mushrooms, nutraceuticals, therapeutic

Abstract

Considering the current situation, relatively little research has been conducted on wild mushrooms to date. Many species of wild mushrooms are found in nature. Discovering new species of these hidden mushrooms, properly identifying them, exploring new compounds hidden in them, and writing new literature would be novel research in the future. In this way, the properties and diversity of wild mushrooms can be further explored. Wild mushrooms can be a valuable new source of pharmacologically active substances, nutraceuticals, and cosmeceuticals, which could be exploited for diverse medical applications in the future, particularly those requiring accurate pharmacogenetic fingerprints. The purpose of the present review study is to compile the information on wild mushrooms discovered by our scientists and researchers from different places and to discuss their medicinal and nutraceutical properties. So accurate data and guidance can be obtained in future research work.

Downloads

Download data is not yet available.

References

Barros, L., Baptista, P., Correia, D. M., Casal, S., Oliveira, B., & Ferreira, I. C. (2007). Fatty acid and sugar compositions, and nutritional value of five wild edible mushrooms from Northeast Portugal. Food Chemistry, 105(1), 140-145. https://doi.org/10.1016/j.foodchem.2007.03.052 DOI: https://doi.org/10.1016/j.foodchem.2007.03.052

Cai, M., Lin, Y., Luo, Y. L., Liang, H. H., & Sun, P. (2015). Extraction, antimicrobial, and antioxidant activities of crude polysaccharides from the wood ear medicinal mushroom Auricularia auricula-judae (higher basidiomycetes). International Journal of Medicinal Mushrooms, 17(6). DOI: https://doi.org/10.1615/IntJMedMushrooms.v17.i6.90

Soumya Chatterjee, S. C., Anwesha Dey, A. D., Riddhi Dutta, R. D., Sandip Dey, S. D., & Krishnendu Acharya, K. A. (2011). Hepatoprotective effect of the ethanolic extract of Calocybe indica on mice with CCl4 hepatic intoxication. International Journal of PharmTech Research 3(4): 2162-2168.

Chen, J., & Seviour, R. (2007). Medicinal importance of fungal β-(1→ 3),(1→ 6)-glucans. Mycological research, 111(6), 635-652. https://doi.org/10.1016/j.mycres.2007.02.011 DOI: https://doi.org/10.1016/j.mycres.2007.02.011

Chowdhury, M. M. H., Kubra, K., & Ahmed, S. R. (2015). Screening of antimicrobial, antioxidant properties and bioactive compounds of some edible mushrooms cultivated in Bangladesh. Annals of clinical microbiology and antimicrobials, 14, 1-6. DOI: https://doi.org/10.1186/s12941-015-0067-3

Chugh, R. M., Mittal, P., Mp, N., Arora, T., Bhattacharya, T., Chopra, H., ... & Gautam, R. K. (2022). Fungal mushrooms: a natural compound with therapeutic applications. Frontiers in pharmacology, 13, 925387. DOI: https://doi.org/10.3389/fphar.2022.925387

De Román, M., Boa, E., & Woodward, S. (2006). Wild gathered fungi for health and rural livelihoods in Europe. Proceedings of the Nutrition Society, 65, 1-8. DOI: https://doi.org/10.1079/PNS2006491

Ding, Q., Yang, D., Zhang, W., Lu, Y., Zhang, M., Wang, L., ... & Chen, Y. (2016). Antioxidant and anti-aging activities of the polysaccharide TLH-3 from Tricholoma lobayense. International Journal of Biological Macromolecules, 85, 133-140. https://doi.org/10.1016/j.ijbiomac.2015.12.058 DOI: https://doi.org/10.1016/j.ijbiomac.2015.12.058

El-Ramady, H., Abdalla, N., Badgar, K., Llanaj, X., Törős, G., Hajdú, P., ... & Prokisch, J. (2022). Edible mushrooms for sustainable and healthy human food: nutritional and medicinal attributes. Sustainability, 14(9), 4941. DOI: https://doi.org/10.3390/su14094941

Finimundy, T. C., Gambato, G., Fontana, R., Camassola, M., Salvador, M., Moura, S., ... & Roesch-Ely, M. (2013). Aqueous extracts of Lentinula edodes and Pleurotus sajor-caju exhibit high antioxidant capability and promising in vitro antitumor activity. Nutrition research, 33(1), 76-84. https://doi.org/10.1016/j.nutres.2012.11.005 DOI: https://doi.org/10.1016/j.nutres.2012.11.005

Gebreyohannes, G., & Sbhatu, D. B. (2023). Wild mushrooms: a hidden treasure of novel bioactive compounds. International Journal of Analytical Chemistry, 2023(1), 6694961. DOI: https://doi.org/10.1155/2023/6694961

Guariguata, L., Whiting, D. R., Hambleton, I., Beagley, J., Linnenkamp, U., & Shaw, J. E. (2014). Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes research and clinical practice, 103(2), 137-149. https://doi.org/10.1016/j.diabres.2013.11.002 DOI: https://doi.org/10.1016/j.diabres.2013.11.002

Heleno, S. A., Barros, L., Sousa, M. J., Martins, A., & Ferreira, I. C. (2010). Tocopherols composition of Portuguese wild mushrooms with antioxidant capacity. Food Chemistry, 119(4), 1443-1450. https://doi.org/10.1016/j.foodchem.2009.09.025 DOI: https://doi.org/10.1016/j.foodchem.2009.09.025

Hemnani, T. A. R. U. N. A., & Parihar, M. S. (1998). Reactive oxygen species and oxidative DNA damage. Indian journal of physiology and pharmacology, 42, 440-452.

Im, K. H., Nguyen, T. K., Choi, J., & Lee, T. S. (2016). In vitro antioxidant, anti-diabetes, anti-dementia, and inflammation inhibitory effect of Trametes pubescens fruiting body extracts. Molecules, 21(5), 639. DOI: https://doi.org/10.3390/molecules21050639

Jander-Shagug, G., & Masaphy, S. (2010). Free radical scavenging activity of culinary-medicinal morel mushrooms, Morchella Dill. ex Pers.(Ascomycetes): relation to color and phenol contents. International journal of medicinal mushrooms, 12(3). DOI: https://doi.org/10.1615/IntJMedMushr.v12.i3.90

Jones, S., & Janardhanan, K. K. (2000). Antioxidant and antitumor activity of Ganoderma lucidum (Curt.: Fr.) P. Karst.—Reishi (Aphyllophoromycetideae) from South India. International Journal of Medicinal Mushrooms, 2(3). DOI: https://doi.org/10.1615/IntJMedMushr.v2.i3.20

Karaman, I., Şahin, F., Güllüce, M., Öǧütçü, H., Şengül, M., & Adıgüzel, A. (2003). Antimicrobial activity of aqueous and methanol extracts of Juniperus oxycedrus L. Journal of ethnopharmacology, 85(2-3), 231-235. https://doi.org/10.1016/S0378-8741(03)00006-0 DOI: https://doi.org/10.1016/S0378-8741(03)00006-0

Kaur, A., Dhingra, G. S., & Shri, R. (2015). Antidiabetic potential of mushrooms. Asian J Pharm Res, 5(2), 111-25.

Krupodorova, T. A., Klymenko, P. P., Barshteyn, V. Y., Leonov, Y. I., Shytikov, D. W., & Orlova, T. N. (2015). Effects of Ganoderma lucidum (Curtis) P. Karst and Crinipellis schevczenkovi Buchalo aqueous extracts on skin wound healing. J. Phytopharmacol, 4(4), 197-201. DOI: https://doi.org/10.31254/phyto.2015.4401

Li, J. W. H., & Vederas, J. C. (2009). Drug discovery and natural products: end of an era or an endless frontier?. Science, 325(5937), 161-165. DOI: https://doi.org/10.1126/science.1168243

Lull, C., Wichers, H. J., & Savelkoul, H. F. (2005). Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators of inflammation, 2005(2), 63-80. DOI: https://doi.org/10.1155/MI.2005.63

Mensink, R. P., Zock, P. L., Kester, A. D., & Katan, M. B. (2003). Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials. The American journal of clinical nutrition, 77(5), 1146-1155. https://doi.org/10.1093/ajcn/77.5.1146 DOI: https://doi.org/10.1093/ajcn/77.5.1146

Mroueh, M., Saab, Y., & Rizkallah, R. (2004). Hepatoprotective activity of Centaurium erythraea on acetaminophen‐induced hepatotoxicity in rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation of Natural Product Derivatives, 18(5), 431-433. DOI: https://doi.org/10.1002/ptr.1498

Panya, M., Kaewraemruaen, C., Saenwang, P., & Pimboon, P. (2024). Evaluation of Prebiotic Potential of Crude Polysaccharides Extracted from Wild Lentinus polychrous and Lentinus squarrosulus and Their Application for a Formulation of a Novel Lyophilized Synbiotic. Foods, 13(2), 287. DOI: https://doi.org/10.3390/foods13020287

Patel, S. H. (2014). Review article on mushroom cultivation. International Journal of Pharmacy Research & Technology (IJPRT), 4(1), 47-59.

Patel, S., & Goyal, A. (2012). Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech, 2, 1-15.

Patel, S., & Goyal, A. (2012). Recent developments in mushrooms as anti-cancer therapeutics: a review. 3 Biotech, 2, 1-15. DOI: https://doi.org/10.1007/s13205-011-0036-2

Pereira, E., Barros, L., Martins, A., & Ferreira, I. C. (2012). Towards chemical and nutritional inventory of Portuguese wild edible mushrooms in different habitats. Food Chemistry, 130(2), 394-403. https://doi.org/10.1016/j.foodchem.2011.07.057 DOI: https://doi.org/10.1016/j.foodchem.2011.07.057

Pilz, D., & Molina, R. (2002). Commercial harvests of edible mushrooms from the forests of the Pacific Northwest United States: issues, management, and monitoring for sustainability. Forest Ecology and management, 155(1-3), 3-16. https://doi.org/10.1016/S0378-1127(01)00543-6 DOI: https://doi.org/10.1016/S0378-1127(01)00543-6

Puttaraju, N. G., Venkateshaiah, S. U., Dharmesh, S. M., Urs, S. M. N., & Somasundaram, R. (2006). Antioxidant activity of indigenous edible mushrooms. Journal of agricultural and food chemistry, 54(26), 9764-9772. DOI: https://doi.org/10.1021/jf0615707

Ramesh, C. H., & Pattar, M. G. (2010). Antimicrobial properties, antioxidant activity and bioactive compounds from six wild edible mushrooms of western ghats of Karnataka, India. Pharmacognosy research, 2(2), 107. DOI: https://doi.org/10.4103/0974-8490.62953

Rushita, S., Vijayakumar, M., Noorlidah, A., Abdulla, M. A., & Vikineswary, S. (2013). Effect of Pleurotus citrinopileatus on blood glucose, insulin and catalase of streptozotocin-induced type 2 diabetes mellitus rats.

Paterson, R. R. M. (2006). Ganoderma–a therapeutic fungal biofactory. Phytochemistry, 67(18), 1985-2001. https://doi.org/10.1016/j.phytochem.2006.07.004 DOI: https://doi.org/10.1016/j.phytochem.2006.07.004

Smolskaitė, L., Venskutonis, P. R., & Talou, T. (2015). Comprehensive evaluation of antioxidant and antimicrobial properties of different mushroom species. LWT-Food Science and Technology, 60(1), 462-471. https://doi.org/10.1016/j.lwt.2014.08.007 DOI: https://doi.org/10.1016/j.lwt.2014.08.007

Soares, M. C. S., Huszar, V. L., Miranda, M. N., Mello, M. M., Roland, F., & Lürling, M. (2013). Cyanobacterial dominance in Brazil: distribution and environmental preferences. Hydrobiologia, 717, 1-12. DOI: https://doi.org/10.1007/s10750-013-1562-1

Srivastava, M. P. (2021). Bio-diversity of Wild Mushrooms and their Future Perspectives. International Journal of Plant and Environment, 7(02), 164-168. DOI: https://doi.org/10.18811/ijpen.v7i02.07

Wasser, S. (2014). Medicinal mushroom science: Current perspectives, advances, evidences, and challenges. Biomedical journal, 37(6). DOI: https://doi.org/10.4103/2319-4170.138318

Wasser, S. J. A. M. B. (2002). Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Applied microbiology and biotechnology, 60, 258-274. DOI: https://doi.org/10.1007/s00253-002-1076-7

Wu, G. S., Guo, J. J., Bao, J. L., Li, X. W., Chen, X. P., Lu, J. J., & Wang, Y. T. (2013). Anti-cancer properties of triterpenoids isolated from Ganoderma lucidum–a review. Expert opinion on investigational drugs, 22(8), 981-992. DOI: https://doi.org/10.1517/13543784.2013.805202

Wu, J. Y., Siu, K. C., & Geng, P. (2021). Bioactive ingredients and medicinal values of Grifola frondosa (Maitake). Foods, 10(1), 95. DOI: https://doi.org/10.3390/foods10010095

Wu, Y., Liu, Y., Wu, J., Ou, K., Huang, Q., Cao, J., ... & Pan, Y. (2022). Chemical profile and antioxidant activity of bidirectional metabolites from Tremella fuciformis and Acanthopanax trifoliatus as assessed using response surface methodology. Frontiers in Nutrition, 9, 1035788. DOI: https://doi.org/10.3389/fnut.2022.1035788

Zhang, H., Wang, Z. Y., Zhang, Z., & Wang, X. (2011). Purified Auricularia auricular-judae polysaccharide (AAP Ia) prevents oxidative stress in an ageing mouse model. Carbohydrate polymers, 84(1), 638-648. https://doi.org/10.1016/j.carbpol.2010.12.044 DOI: https://doi.org/10.1016/j.carbpol.2010.12.044

Zhang, N., Chen, H., Zhang, Y., Ma, L., & Xu, X. (2013). Comparative studies on chemical parameters and antioxidant properties of stipes and caps of shiitake mushroom as affected by different drying methods. Journal of the Science of Food and Agriculture, 93(12), 3107-3113. DOI: https://doi.org/10.1002/jsfa.6151