Assessment of IL-8 and CBC in people working in LPG stations in Najaf Province

Bahaa Ul-deen Jwaad; Alaauldeen S. M. ALsallami

doi:10.53730/ijhs.v6nS5.9017

Authors

Bahaa Ul-deen Jwaad Department of Biology, Faculty of Science, University of Kufa, Iraq
Alaauldeen S.M. ALsallami Department of Biology, Faculty of Science, University of Kufa, Iraq

Keywords:

IL-8, CBC, LPG

Abstract

A comparative cross-sectional study was conducted on LPG stations workers in Najaf City, Iraq from December 2021 to January 2022. In which workers exposed liquefied petroleum gas (LPG) were compared with individuals who were not exposed (control group). The LPG gas plant workers were all males who work between 8 am to 2 pm daily. A total of eighty-eight (88) subjects took part in this study (control groups, n= 38 and workers, n=50) their mean age of workers 32.04 ± 1.289 years and for control 33.39 ± 1.680 years. In this study, and the mean Body Mean Index (BMI) of workers (27.30 ± 0.4479), and for control (27.87± 0.8296). The result showed a significant (P<0.05) and clear increase in the level of interleukin-8 of workers (1.538±0.4359pg/ml) compared to the control group (0.4138±0.02580 pg/ml).

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References

Al-Masaoodi, Rusul Ali ; Al-Sallami, Alaauldeen S. M. ; Al-Baseesee, Hamadallah.(2019). The relation between the RANKL and resistin in menopausal women with osteoporosis. The 7th International Conference on Applied Science and Technology (ICAST 2019) AIP Conf. Proc. 2144, 040012-1–040012-13; https://doi.org/10.1063/1.5123113.

Al-Msaid, Hayder L.F. & Al-Sallami, Alaauldeen S.M.(2018). Study the level of cytokine in unexplained and idiopathic infertile men. Journal of Pharmaceutical Sciences and Research. Vol. 10(4), pp808-811.

AL-Sallami, Alaauldeen S.M. & Al-Shimerty, Dhirgam F. Hassan.(2021). EFFECT OF ANTIPHOSPHOLIPID IN IRAQI WOMEN UNDERGOING ICSI TECHNIQUE. International Journal of Health and Life-Sciences. Volume 7 Issue 2, pp. 60-68. DOI- https://dx.doi.org/10.20319/lijhls.2021.72.6068.

B.N., O., K.O., I., I.U., I., T.J, O., S.A., A., E.R., U., A.H., B., L.E., O., & I.A., O. (2020). Effects of Duration of Exposure on Biochemical and Haematological Profile in Liquefied Petroleum Gas (LPG) Plant Workers. International Journal of Research Publications, 58(1), 1–8. https://doi.org/10.47119/ijrp100581820201352

Cai, B.N., O., K.O., I., I.U., I., T.J, O., S.A., A., E.R., U., A.H., B., L.E., O., & I.A., O. (2020). Effects of Duration of Exposure on Biochemical and Haematological Profile in Liquefied Petroleum Gas (LPG) Plant Workers. International Journal of Research Publications, 58(1), 1–8. https://doi.org/10.47119/ijrp100581820201352

Cesta, M. C., Zippoli, M., Marsiglia, C., Gavioli, E. M., Mantelli, F., Allegretti, M., & Balk, R. A. (2022). The Role of Interleukin-8 in Lung Inflammation and Injury: Implications for the Management of COVID-19 and Hyperinflammatory Acute Respiratory Distress Syndrome. Frontiers in Pharmacology, 12(January), 1–7. https://doi.org/10.3389/fphar.2021.808797

Che, L., Yu, C., Chen, G., Lin, J., Xie, Z., Xia, T., Luo, W., Cai, X., & Liu, S. (2021). The inflammatory response induced by relmβ upregulates il-8 and il-1β expression in bronchial epithelial cells in copd. International Journal of COPD, 16(May), 2503–2513. https://doi.org/10.2147/COPD.S321877

E, A. A. P. (2021). Potential Health Effects due to Exposure of Chaitanya P 1 , Upadhyay E 1 *, Criteria Air Pollutants Singh DD and Singh V Abstract Abbreviations : Health Science Journal, 15, 1–13.

Fukunagaa, T., & Yamamoto, H. (1996). Liquefied petroleum gas ( LPG ) poisoning : report of two cases and review of the literature. 82, 193–200.

Hall, J. E., & Hall, M. E. (2020). Guyton and Hall Textbook of Medical Physiology E-Book. https://books.google.co.id/books?id=H1rrDwAAQBAJ

Hay, D. W. P., & Sarau, H. M. (2001). Interleukin-8 receptor antagonists in pulmonary diseases. 242–248.

Jo, J. Y., Kwon, Y. S., Lee, J. W., Park, J. S., Rho, B. H., & Choi, W. Il. (2013). Acute respiratory distress due to methane inhalation. Tuberculosis and Respiratory Diseases, 74(3), 120–123. https://doi.org/10.4046/trd.2013.74.3.120

L., Rubin, J., Han, W., Venge, P., & Xu, S. (2010). The origin of multiple molecular forms in urine of HNL/NGAL. Clinical Journal of the American Society of Nephrology, 5(12), 2229-2235

McElvaney, N. G., Nakamura, H., Birrer, P., Hébert, C. A., Wong, W. L., Alphonso, M., Baker, J. B., Catalano, M. A., & Crystal, R. G. (1992). Modulation of airway inflammation in cystic fibrosis: In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor. Journal of Clinical Investigation, 90(4), 1296–1301. https://doi.org/10.1172/JCI115994

Mukaida, N. (2003). Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. American Journal of Physiology - Lung Cellular and Molecular Physiology, 284(4 28-4), 566–577. https://doi.org/10.1152/ajplung.00233.2002

Nicod, L. P. (2005). Lung defences : an overview. 14(95), 45–50. https://doi.org/10.1183/09059180.05.00009501

Nyabuto, J. K., Mburu, C., & Gichuhi, M. (2020). Awareness of Occupational Safety and Health Issues in Liquefied Petroleum Gas Business in Kiambu County, Kenya. International Journal of Scientific and Research Publications (IJSRP), 10(4), p10003. https://doi.org/10.29322/ijsrp.10.04.2020.p10003

Olamigoke, O. (2019). Quantitative Hazard Analysis of Liquefied Petroleum Gas Bottling Plants : A Case Study. Nigerian Society of Chemical Engineers, November, 1–7.

Saadat, M., Bahaoddini, A., & Nazemi, S. (2004). Alterations in blood pressure due to chronic exposure to natural sour gas leakage containing sulfur compounds. 313, 568–569. https://doi.org/10.1016/j.bbrc.2003.11.155

Sharif, D. A., Awn, A. H., Murad, K. M., & Meran, I. M. (2017). Demographic and characteristic distribution of end-stage renal failure in Sulaimani Governate, Kurdistan region, Iraq. Int J Med Res Prof, 3, 155-8.

Suega, K., Bakta, M., Dharmayudha, T. G., Lukman, J. S., & Suwitra, K. (2005). Profile of anemia in chronic renal failure patients: comparison between predialyzed and dialyzed patients at the Division of Nephrology, Department of Internal Medicine, Sanglah Hospital, Denpasar, Bali, Indonesia. inflammation, 1, 6-9.

Sugie, H., Sasaki, C., Hashimoto, C., Takeshita, H., Nagai, T., Nakamura, S., Furukawa, M., Nishikawa, T., & Kurihara, K. (2004). Three cases of sudden death due to butane or propane gas inhalation: Analysis of tissues for gas components. Forensic Science International, 143(2–3), 211–214. https://doi.org/10.1016/j.forsciint.2004.02.038

Thompson, L. M. (2015). Cooking with gas : How children in the developing world benefit from switching to LPG. September, 1–50.

Ukaejiofo, E. O., Nubila, T., & Ike, S. O. (2006). Biochemical and haematological assessment of workers exposed to some petroleum products in Rnugu Urban, Rnugu State, Nigeria. Nigerian Journal of Medicine : Journal of the National Association of Resident Doctors of Nigeria, 15(3), 318–322. https://doi.org/10.4314/njm.v15i3.37239

Waugh, D. J. J., & Wilson, C. (2008). The interleukin-8 pathway in cancer. Clinical Cancer Research, 14(21), 6735–6741. https://doi.org/10.1158/1078-0432.CCR-07-4843

Wu, A. H. B., Mckay, C., Broussard, L. A., Hoffman, R. S., Kwong, T. C., Moyer, T. P., Otten, E. M., Welch, S. L., & Wax, P. (2003). National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines : Recommendations for the Use of Laboratory Tests to Support Poisoned Patients Who Present to the Emergency Department. 379, 357–379.