Antidiabetic and antihyperglycemic effect of citrus

Mohammed Mosleh Shwaish; Warda Theab Farhan; Tasnim Tariq Mohammed

doi:10.53730/ijhs.v6nS2.7112

Authors

Mohammed Mosleh Shwaish
dr.mohammed99@uofallujah.edu.iq
Department of Physiology, Biochemistry and Pharmacology, University of Fallujah, Iraq
Warda Theab Farhan Department of Pharmacy, Al-Maarif University College, Iraq
Tasnim Tariq Mohammed Department of Medical Lab. technique, Al-Maarif University College, Iraq

Keywords:

citrus, chemistry citrus, pharmacological profile, diabetes mellitus, anti-diabetics effect, hyperlipidemia, anti-hyperlipidemia effects

Abstract

The tangerine fruit peels of Citrus reticulata contain significant amounts of three flavanones: hesperidin, naringin, and narirutin. Citrus is a rue group species of blooming trees and shrubs. In contrast to flavonol and quercetinRutaceae, citrus peel complex compounds quantities of flavonol and quercetinRutaceae. DM is one of most chronic diseases in the world. Citrus reticulata is a kind of citrus fruit with a various degrees of Hesperidin, a glycosylated flavanone of hesperetin, suppresses gluconeogenic pathways and diminishes intestinal glucose absorption in diabetes patients, leading in anti-hyperglycemic properties. Recent research looks into the efficacy of naringin to improve cholesterol levels by reducing HMGCoA reductase. Citrus sinensis, Citrus paradisi, and their combination have antihyperlipidemic and antiatherosclerosis properties. Hyperlipidemia is a collection of disorders characterized by elevated blood levels of lipids and lipoproteins, such as cholesterol, low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL), which can lead to atherosclerosis. Atherosclerosis and coronary heart disease (CHD) are the leading causes of death and sickness around the world.

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