Perioperative outcomes of minimally invasive coronary artery bypass grafting over conventional sternotomy: A propensity-matched analysis
Keywords:
cardiac surgical procedures, minimally invasive surgical procedures, coronary artery disease, myocardial revascularization, propensity scoreAbstract
Background: A minimally invasive coronary artery bypass grafting (MICS CABG) procedure has been devised as a less invasive alternative to conventional open sternotomy (OPEN CABG) through a left anterior thoracotomy. The objective of this investigation was to employ propensity score matching to compare the procedural characteristics, ventilation duration, drainage volumes, and postoperative complications of MICS CABG and OPEN CABG. Methods: This retrospective propensity-matched study was performed on 350 cases who were subjected to surgical revascularization from January 2017 to June 2021. Propensity score matching (1:1 nearest-neighbor) was conducted to control for baseline differences. Results: 175 patients were included in each cohort following propensity matching. MICS CABG was related to a shortened median procedure time (p = 0.03) and a decreased mechanical ventilation duration (5p < 0.001). MICS CABG resulted in a shorter total hospitalisation (p = 0.04). Transfusion requirements for red blood cells were decreased (p = 0.04), and postoperative drainage was substantially reduced at 12 hours (p < 0.01). MICS CABG was related to a lower incidence of acute kidney injury (p = 0.03). Conclusions: MICS CABG should be considered as a preferred approach for coronary revascularization in cases with appropriate anatomy and disease complexity.
Downloads
References
Organization WH. World Health Organization cardiovascular diseases (CVDs) fact sheet. World Health Organ. 2020;42:207-16.
Libby P, Theroux P. Pathophysiology of coronary artery disease. Circulation. 2005;111:3481-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.537878
Head SJ, Milojevic M, Daemen J, Ahn JM, Boersma E, Christiansen EH, et al. Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data. Lancet. 2018;391:939-48. DOI: https://doi.org/10.1016/S0140-6736(18)30423-9
Diegeler A, Matin M, Kayser S, Binner C, Autschbach R, Battellini R, et al. Angiographic results after minimally invasive coronary bypass grafting using the minimally invasive direct coronary bypass grafting (MIDCAB) approach. Eur J Cardiothorac Surg. 1999;15:680-4. DOI: https://doi.org/10.1016/S1010-7940(99)00004-4
McGinn JT, Jr., Usman S, Lapierre H, Pothula VR, Mesana TG, Ruel M. Minimally invasive coronary artery bypass grafting: dual-center experience in 450 consecutive patients. Circulation. 2009;120:S78-84. DOI: https://doi.org/10.1161/CIRCULATIONAHA.108.840041
Ruel M, Une D, Bonatti J, McGinn JT. Minimally invasive coronary artery bypass grafting: is it time for the robot? Curr Opin Cardiol. 2013;28:639-45. DOI: https://doi.org/10.1097/HCO.0b013e3283653fd1
Teman NR, Hawkins RB, Charles EJ, Mehaffey JH, Speir AM, Quader MA, et al. Minimally Invasive vs Open Coronary Surgery: A Multi-Institutional Analysis of Cost and Outcomes. Ann Thorac Surg. 2021;111:1478-84. DOI: https://doi.org/10.1016/j.athoracsur.2020.06.136
Stanislawski R, Aboul-Hassan SS, Marczak J, Stankowski T, Peksa M, Nawotka M, et al. Early and long-term clinical outcomes after minimally invasive direct coronary artery bypass grafting versus off-pump coronary surgery via sternotomy in isolated proximal left anterior descending artery disease: A propensity score matching analysis. J Card Surg. 2020;35:3412-9. DOI: https://doi.org/10.1111/jocs.15056
Mastroiacovo G, Manganiello S, Pirola S, Tedesco C, Cavallotti L, Antona C, et al. Very Long-term Outcome of Minimally Invasive Direct Coronary Artery Bypass. Ann Thorac Surg. 2021;111:845-52. DOI: https://doi.org/10.1016/j.athoracsur.2020.06.025
Puskas JD, Edwards FH, Pappas PA, O'Brien S, Peterson ED, Kilgo P, et al. Off-pump techniques benefit men and women and narrow the disparity in mortality after coronary bypass grafting. Ann Thorac Surg. 2007;84:1447-54. DOI: https://doi.org/10.1016/j.athoracsur.2007.06.104
Mohamed MA, Ding S, Ali Shah SZ, Li R, Dirie NI, Cheng C, et al. Comparative Evaluation of the Incidence of Postoperative Pulmonary Complications After Minimally Invasive Valve Surgery vs. Full Sternotomy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Propensity Score-Matched Studies. Front Cardiovasc Med. 2021;8:724178. DOI: https://doi.org/10.3389/fcvm.2021.724178
Olbrecht VA, Barreiro CJ, Bonde PN, Williams JA, Baumgartner WA, Gott VL, et al. Clinical outcomes of noninfectious sternal dehiscence after median sternotomy. Ann Thorac Surg. 2006;82:902-7. DOI: https://doi.org/10.1016/j.athoracsur.2006.04.058
Despotis GJ, Filos KS, Zoys TN, Hogue CW, Jr., Spitznagel E, Lappas DG. Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients. Anesth Analg. 1996;82:13-21. DOI: https://doi.org/10.1097/00000539-199601000-00004
Murphy GJ, Reeves BC, Rogers CA, Rizvi SI, Culliford L, Angelini GD. Increased mortality, postoperative morbidity, and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007;116:2544-52. DOI: https://doi.org/10.1161/CIRCULATIONAHA.107.698977
Koch CG, Li L, Duncan AI, Mihaljevic T, Cosgrove DM, Loop FD, et al. Morbidity and mortality risk associated with red blood cell and blood-component transfusion in isolated coronary artery bypass grafting. Crit Care Med. 2006;34:1608-16. DOI: https://doi.org/10.1097/01.CCM.0000217920.48559.D8
Shander A, Hofmann A, Gombotz H, Theusinger OM, Spahn DR. Estimating the cost of blood: past, present, and future directions. Best Pract Res Clin Anaesthesiol. 2007;21:271-89. DOI: https://doi.org/10.1016/j.bpa.2007.01.002
Paparella D, Yau TM, Young E. Cardiopulmonary bypass induced inflammation: pathophysiology and treatment. An update. Eur J Cardiothorac Surg. 2002;21:232-44. DOI: https://doi.org/10.1016/S1010-7940(01)01099-5
Puskas JD, Williams WH, Mahoney EM, Huber PR, Block PC, Duke PG, et al. Off-pump vs conventional coronary artery bypass grafting: early and 1-year graft patency, cost, and quality-of-life outcomes: a randomized trial. Jama. 2004;291:1841-9. DOI: https://doi.org/10.1001/jama.291.15.1841
Lagny MG, Jouret F, Koch JN, Blaffart F, Donneau AF, Albert A, et al. Incidence and outcomes of acute kidney injury after cardiac surgery using either criteria of the RIFLE classification. BMC Nephrol. 2015;16:76. DOI: https://doi.org/10.1186/s12882-015-0066-9
Mao H, Katz N, Ariyanon W, Blanca-Martos L, Adýbelli Z, Giuliani A, et al. Cardiac surgery-associated acute kidney injury. Cardiorenal Med. 2013;3:178-99. DOI: https://doi.org/10.1159/000353134
Karkouti K. Transfusion and risk of acute kidney injury in cardiac surgery. Br J Anaesth. 2012;109 Suppl 1:i29-i38. DOI: https://doi.org/10.1093/bja/aes422
Kumar AB, Suneja M, Bayman EO, Weide GD, Tarasi M. Association between postoperative acute kidney injury and duration of cardiopulmonary bypass: a meta-analysis. J Cardiothorac Vasc Anesth. 2012;26:64-9. DOI: https://doi.org/10.1053/j.jvca.2011.07.007
Bellomo R, Kellum JA, Ronco C. Acute kidney injury. The Lancet. 2012;380:756-66. DOI: https://doi.org/10.1016/S0140-6736(11)61454-2
Hix JK, Thakar CV, Katz EM, Yared JP, Sabik J, Paganini EP. Effect of off-pump coronary artery bypass graft surgery on postoperative acute kidney injury and mortality. Crit Care Med. 2006;34:2979-83. DOI: https://doi.org/10.1097/01.CCM.0000248905.67352.BA
Seabra VF, Alobaidi S, Balk EM, Poon AH, Jaber BL. Off-pump coronary artery bypass surgery and acute kidney injury: a meta-analysis of randomized controlled trials. Clin J Am Soc Nephrol. 2010;5:1734-44. DOI: https://doi.org/10.2215/CJN.02800310
Imazio M, Trinchero R, Brucato A, Rovere ME, Gandino A, Cemin R, et al. COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placebo-controlled trial. Eur Heart J. 2010;31:2749-54. DOI: https://doi.org/10.1093/eurheartj/ehq319
Mathew JP, Fontes ML, Tudor IC, Ramsay J, Duke P, Mazer CD, et al. A multicenter risk index for atrial fibrillation after cardiac surgery. Jama. 2004;291:1720-9. DOI: https://doi.org/10.1001/jama.291.14.1720
Sarr MG, Gott VL, Townsend TR. Mediastinal infection after cardiac surgery. Ann Thorac Surg. 1984;38:415-23. DOI: https://doi.org/10.1016/S0003-4975(10)62300-4
Braxton JH, Marrin CA, McGrath PD, Morton JR, Norotsky M, Charlesworth DC, et al. 10-year follow-up of patients with and without mediastinitis. Semin Thorac Cardiovasc Surg. 2004;16:70-6. DOI: https://doi.org/10.1053/j.semtcvs.2004.01.006
Panesar SS, Athanasiou T, Nair S, Rao C, Jones C, Nicolaou M, et al. Early outcomes in the elderly: a meta-analysis of 4921 patients undergoing coronary artery bypass grafting--comparison between off-pump and on-pump techniques. Heart. 2006;92:1808-16. DOI: https://doi.org/10.1136/hrt.2006.088450
Bakaeen FG, Shroyer AL, Gammie JS, Sabik JF, Cornwell LD, Coselli JS, et al. Trends in use of off-pump coronary artery bypass grafting: Results from the Society of Thoracic Surgeons Adult Cardiac Surgery Database. J Thorac Cardiovasc Surg. 2014;148:856-3, 64.e1; discussion 63-4. DOI: https://doi.org/10.1016/j.jtcvs.2013.12.047
Baishya J, George A, Krishnamoorthy J, Muniraju G, Chakravarthy M. Minimally invasive compared to conventional approach for coronary artery bypass grafting improves outcome. Ann Card Anaesth. 2017;20:57-60. DOI: https://doi.org/10.4103/0971-9784.197837
Published
How to Cite
Issue
Section
Copyright (c) 2021 International journal of health sciences

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.








