Dynamics changes of hematological and in predicting mortality in severe COVID-19
Keywords:
hematological markers, predicting, mortality, severe COVID-19Abstract
Introduction: COVID-19 pandemic has been a challenge. Biomarkers have always played an important role in clinical decision making in various infectious diseases. It is crucial to assess the role of biomarkers in evaluating severity of disease and appropriate allocation of resources. The aim of study is to evaluate association between biomarkers and outcomes in COVID-19 hospitalized patients. Methods: We conducted a retrospective study of 100 patients admitted with severe COVID-19 in Dar-Alsalam hospital, Baghdad, from January to July 2021. We obtained their clinical, and biochemical characteristics at baseline and we fallow up for 20 days after admission with 4 days’ interval. The data were analyzed to determine the prognostic significance of these markers on the final outcome. Results: the mean age(years) was 56.79 ± 11.717 years with range (29-77) years. Gender: 39(39%) patients were female and 61(61%) of them were male. 50(50%) patients survived and 50(50%) of them not survived. WBC (10"3/ul) was significantly higher in day8, 12,16 and 20, Lymphocytes (10"3/ul) was significantly lower in non-survived patients during all follow-up days, Neutrophils (10"3/ul) was significantly higher in day8, 12,16 and 20, N/L Ratio was significantly higher in day1, 4,16 and 20 (15.42, 17.96, 42.48 and 59.64) respectively.
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