Study of clinical profile of hypothyroidism in a tertiary care hospital, Central India

Abstract

Background: hypothyroidism is a common disorder in overweight Indian female populations.  Comorbidities and complications are more in patients with hypothyroidism compared to other people. Hence early diagnosis and early treatment for hypothyroidism can prevent a lot of complications in patients, especially for subclinical hypothyroidism. Aim and Objective: To study the presentation and clinical profile of hypothyroidism in central Indian population. Material &Methods: this cross sectional study was carried out among 240 clinically diagnosed patients of hypothyroidism in a tertiary care centre, Madhya Pradesh, India. Thorough history and clinical examination was done to ascertain the clinical features. Results: females had a higher (71.7%) incidence of hypothyroidism than male. Most common symptoms are of weakness, weight gain, facial puffiness, irritability, hair loss and menstrual irregularities. On general examination most common findings are weight gain, pallor, dry skin, pedal edema and Goiter. Type 2 diabetes mellitus, dyslipidemia, obesity and hypertension were commonly associated with the hypothyroidism. Conclusions: hypothyroidism most common in older age females. Weight gain, weakness, facial puffiness, pedal edema, falling of hair, pallor and menstrual irregularities was the common clinical presentation of hypothyroidism