International Journal of Health Sciences <p style="text-align: justify;"><strong>IJHS</strong>&nbsp;is published in English and it is open to authors around the world regardless of the nationality. It is currently published three times a year, i.e. in&nbsp;<em>April</em>,&nbsp;<em>August</em>, and&nbsp;<em>December</em>.&nbsp;</p> en-US (Prof. Dr. Marioneya Izaguirre Bordelois) (Vedran Vucic) Fri, 31 Aug 2018 00:00:00 +0000 OJS 60 High level of tumor necrosis alpha and serum interferon gamma as risk factors for progression of vitiligo disease <p style="text-align: justify;">Vitiligo is an autoimmune disease that causes melanocyte of dysfunction. Cytokines played an important role in the pathogenesis of vitiligo. <em>Interferon-gamma </em>and TNF-µ&nbsp; were cytokines that induce apoptosis of melanocyte cell. The increase of cytokine levels affects the clinical course of vitiligo. The stable and progressive phase of vitiligo clinically is not easy to predict. Assessment of vitiligo stability could be used to determine treatment options, duration of therapy and prognosis. This study was a cross-sectional observational study which intended to prove high levels of TNF-? and IFN-g serum is a risk factor for vitiligo progression. The demographic, clinical, and laboratory data in active vitiligo subjects (n=30) were compared with stable vitiligo subjects&nbsp;&nbsp; (n=40).&nbsp;&nbsp; The relationship was analyzed with multivariate. Median of the subject age with active vitiligo was 44 years (8~60) and on the subject with stable vitiligo was 45 years (15~66). The most subjects were male (58.5%) and the most common type of vitiligo was non-segmental vitiligo (87.1%). Multivariate analysis showed a high level of TNF-µ serum increased the risk of vitiligo progressivity (Adjusted PR 390.89; CI 95 % 27.98-5460.12 ; p&lt;0,001) and high level of IFN-g serum increased the risk of vitiligo progressivity (Adjusted PR 341.06; CI 95% 33.40-3482.26 ; p&lt;0,001). The high level of TNF-µ and IFN-g serum as a risk factor for progression of vitiligo could be used to assess the activity of vitiligo disease. The further research about the association between TNF-µ&nbsp; and IFN-g to predict the therapeutic response in vitiligo.</p> IGAA Praharsini, Nyoman Suryawati, IGAA Ellis Indira, Saraswati Prima Sanjiwani ##submission.copyrightStatement## Mon, 23 Apr 2018 01:47:09 +0000 Lipid profile in obese children with and without insulin resistance <p style="text-align: justify;">Obesity is increasing nowadays including in children and there is lack of information on the pathophysiology and their complication such as insulin resistance and dyslipidemia. This study was aimed to investigate the comparison of lipid profile in obese children with and without insulin resistance. A crossectional study held at an elementary school in Denpasar, Bali from August until September 2015. Independent t-test, Mann-Whitney test, and Multivariate analysis of covariance (MANCOVA) were performed to compare lipid profile in obese children with and without insulin resistance. A P-value less than 0.05 was considered statistically significant. A total of 50 obese children were analyzed. In this study, we found 12 subjects (24%) with insulin resistance. Nonsignificant associations were found between insulin resistance with total cholesterol, HDL, LDL, and ratio of HDL/LDL. A significant association was found between insulin resistance and triglyceride level after adjusted age and sex. There was a significant mean difference of triglycerides in the insulin resistance and noninsulin resistance groups in obese children.</p> Novita Tjiang, I Gusti Lanang Sidiartha ##submission.copyrightStatement## Mon, 23 Apr 2018 00:00:00 +0000 Implementation of STRONGkids in identify risk of malnutrition in government hospital <p style="text-align: justify;">Hospital malnutrition increase morbidity and mortality rate of hospitalized children, regardless of underlying diseases. This study evaluated the risk of malnutrition using STRONGkids screening tool in hospitalized children in government hospitals. An observational study was done in seven government hospitals in Bali, Indonesia. The STRONGkids score of consecutively hospitalized children was calculated and compared with the nutritional status, age, gender, and underlying diseases. Chi-Square and Logistic Regression test were done with considered significant if P-value &lt; 0.05.&nbsp; Total 129 children included in this study. Fifty-six percent of males, mean age 4.1&lt;3.4 years, 20.3% had an underlying chronically diseases, 6.2% had severe malnutrition, and 25.6% had moderate malnutrition. Based on STRONGkids, 12.4% children were at high risk and 87.6% at moderate risk without at low risk for malnutrition. High risk for malnutrition was associated with chronically diseases (p= 0.020), severe and moderate malnutrition (p = 0.001 and p = 0.012, respectively). It can be concluded that the STRONGkids can be recommended in identify the risk of malnutrition in hospitalized children. Children with high or moderate risk for malnutrition need nutritional support such as high energy density oral supplementation.</p> I Gusti Lanang Sidiartha, I Gusti Ayu Putu Eka Pratiwi ##submission.copyrightStatement## Thu, 03 May 2018 10:28:18 +0000 Homeopathy for breast cancer treatment towards Hindu women <p style="text-align: justify;">This study was intended to reveal the facts regarding homeopathy in the breast cancer treatment for Hindu women in Buleleng regency. Through qualitative research methods, phenomenology theory, power and knowledge relation, health-seeking behavior, and the theory of health believe and explanatory model can reveal the reasons underlying the homeopathy occurrence in the breast cancer treatment, i.e., low medical awareness, accumulated awareness of praxis, and chemotherapy, confidence and treatment behaviors. Homeopathic practices in the breast cancer treatment included <em>Balian</em>/shaman (Balinese spiritual) as a traditional Balinese homeopath, breast cancer etiology, disease diagnosis, preliminary therapy, core therapy, and advanced therapy, and cure categories. Homeopathy in the breast cancer treatment has implications for the sustainability of the traditional Balinese treatment culture; implicates the patient in three ways, e.g., the delay and increased stage of cancer, giving psychic comfort to the patient without positive effects for healing, and providing psychic comfort as well as positive effects for healing; has medical implications as the antithesis of medical systems, media of reflection and instruction for the medical, and the desire emergence for some medical circles to combine medical and nonmedical.</p> I Ketut Suparna, A.A. Ngurah Anom Kumbara, Ida Bagus Darmika ##submission.copyrightStatement## Sun, 06 May 2018 15:31:47 +0000 Recurrence related factors of febrile seizure <p style="text-align: justify;">Febrile seizure was the most common form of childhood seizures, affecting 2-5% of children aged 6 months until five years. They are considered benign and self-limiting, but some cases may recur up to 80%. Identified the recurrence related factors are important to determine prognoses and therapies. Aims of this study were to know the prevalence of febrile seizure in Sanglah hospital and it’s recurrence related factors. A crossectional study design to investigate febrile seizure cases in the pediatric department, Sanglah Hospital. Five recurrent related factors were identified and analyzed, prevalently related counted.&nbsp; In this study, 100 subjects were enrolled. The prevalence was 1.5% in patients age 6 months until 5 years. Twenty-six subjects (26%) with a recurrent febrile seizure. Bivariate analysis obtained a recurrence febrile seizure occurred 1.5 (CI 95% 0.77-2.95) in patients suffering from first seizures at less than 12 month; 1.75 (CI 95% 0.9-3.38) in patient with temperature below 39°C; and 2.44 (CI 95% 1.3-4.57) occurred in patient with a positive history of febrile seizure or epilepsy at 1st degree family. The significant related factor for recurrence is a positive history of febrile seizure or epilepsy at the 1st-degree relative.</p> Ni Putu Yunik Novayanti, Dewi Sutriani Mahalini, I Gusti Ngurah Made Suwarba ##submission.copyrightStatement## Fri, 29 Jun 2018 09:34:12 +0000 Adult women perception towards obesity and its intervention strategies in the community <p style="text-align: justify;">Obesity was one of the health problems experienced in the society, especially in adult women and the number was increasing rapidly every year. The various factors contribute to the obesity occurrence in adult women and appropriate obesity prevention strategies must be taken. With reference to being needed exploring the obesity perception, its causes, and impact as well as countermeasures strategies based on the needs of the society itself. The study was intended to explore the society perception regarding obesity, ideal weight, and strategies that the society wanted in overcoming obesity. The study was a qualitative study. It was conducted in March-July 2017. The research subjects (participants) were women 25-50 years old, the leader of the Family Welfare education organization, and health workers (nutritionist) in Denpasar city about 22 people. The data were collected included obesity and weight perception, social determinants, the impact of obesity and opinions on obesity prevention strategies. The data were collected through the Focus Group Discussion (FGD) process in adult women, in-depth interviews with the leader of the Family Welfare education organization, and society leaders. It was analyzed and presented descriptively. The results showed that most of the participants stated obesity was identical to overweight. Obesity was a health problem that has an impact on the onset of chronic diseases e.g., diabetes, therefore, less of confidence self. An ideal weight was proportional become a desire. The most participants perceived themselves as fat and far from ideal. They did not want to be fat, however, the various inhibiting factors, unlike dietary habit, were difficult to change, the availability of fast food that was very easily accessible, work, less of exercise, transportation occurred lack of movement. They generally want a comprehensive program through eating arrangements, exercise regularly, education at improving knowledge, and education at balancing menu processing skills. It was carried out together by involving social groups in the community.</p> Ni Komang Wiardani, IGP Adiatmika, Diah Pradnya Paramita, Ketut Tirtayasa ##submission.copyrightStatement## Sat, 11 Aug 2018 05:47:02 +0000 Physiological and psychosocial change and the need of health intervention model for elderly <p style="text-align: justify;">Elderly was the final stage of the human life cycle. The humans would surely experience change physically and mentally. The physiological needs were a very primary need and absolutely ought to be fulfilled to maintain biological homeostasis and survival for each human being. The research was intended to explore physiological and psychosocial changes occurred in the elderly and the health intervention model. It was most likely to be received by the elderly in Tabanan Regency, Bali Province. A qualitative method was applied in the present study based on the phenomenological design approach. The sample in the present study was taken a maximum variation. The research subject displayed many variations, data collection was obtained from in-depth interviewed, focused group discussions and observation. The results of the study indicated that the respondents had experienced physiological change. The more age cause of the ability and distrust of others towards the expressed diseases. The research was expected to improve the quality of the old life, depending on health aspects. It, therefore, was very important to develop an elderly health intervention program. It was designed to their needs and desires. The program would be easily accepted if they really thought was important.</p> Diah Pradnya Paramita, IGP Adiatmika, Tuty Kuswardhani, I Wayan Mustika ##submission.copyrightStatement## Mon, 13 Aug 2018 14:46:32 +0000 High risk of HIV towards sexual transaction, use of drugs, and lingual symbol of day-pay workers <p style="text-align: justify;">The number of people suffering from HIV/AIDS increases from year to year in Padang City. The two main causes are free sex and drug use. One of the most frequent subpopulations of free sex and drug use is a day-pay worker in Teluk Bayur Seaport. They have their own lingual behaviors, patterns, and symbols for the sexual transaction and drug use. These are the aspects discussed in this paper. A qualitative study with a trans-sectional non-experimental design was applied. Data were collected through interviews, existing documents, and social networks. A thematic content analysis is used to analyze. The results proved the opportunity to commit free sex and drug use in Teluk Bayur Seaport is in the waiting period of the ship arrival. The most frequently used locations are on boats, on trucks, and wild lodges around the seaport. Types of drugs with the use of hypodermic needles are thought of to be potentially high in HIV infection. Research has also proven that day-pay workers at Teluk Bayur Seaport use lingual symbols and numeric symbols in sexual transactions and drug use.</p> Yessy Markolinda, - Sawirman ##submission.copyrightStatement## Wed, 15 Aug 2018 13:51:14 +0000 Verification of dosage and radiation delivery time breast cancer (Mammae Ca) with ISIS TPS <p style="text-align: justify;">Cancer was a disease caused of the abnormal growth of cells of body tissue turned to the cancer cells. For its development, these cancer cells can spread to other parts of the body, therefore, they can be the cause of the death. Cancer was a general term for all types of malignant tumors. It was one of the diseases required radiation therapy, namely breast cancer (<em>mamma ca</em>), wherein the breast cancer was the second type of cancer that causes of the death after cervical cancer for women. Radiotherapy was a cancer therapy used radiation sources at aiming to shrink and kill cancer cells as much as possible through the provision of the measured radiation doses on the tumor volume/target as well as to minimize the effects of the radiation on the healthy tissue around the tumor. The purpose of verification was to determine the suitability between the dose and time of irradiation of the radiation received by the patient with the radiation dose and irradiation time planned, thus, as not to experience a shortage or excess dosage and radiation irradiation time. The measurement of the dose and radiation irradiation time using constant <em>Source to Surface Distance (SSD)</em> techniques. The section handling the problem of the cancer therapy at Sanglah Hospital was in the Radiotherapy section of Radiology Installation. It was equipped with various medical support equipment, <em>i.e,</em> ISIS polling stations that conform to standard standards. The ideal dose criteria based on the <em>isodoses</em> curve was 95% minimal and 107% maximum about the target. The dose distribution was homogeneous. If the target dose has covered 100% then it can be stated that the plan was optimal. The verification of the dosage and time with ISIS TPS was in accordance with the Republic of Indonesia Minister of Health Regulation No. 363/Menkes/Per/IV/1998.</p> Gusti Ngurah Sutapa, I Made Yuliara, Ni Nyoman Ratini ##submission.copyrightStatement## Tue, 28 Aug 2018 07:44:48 +0000