Effect of Plasmodium vivax malaria and their density on some Haematological parameters in infected patients admitted to Wad Medani teaching hospital in Gezira state, Sudan

Albadawi A Talha; Abozer Y Elderdery; Esraa A. Goda; Adam D A Salim; Lana M Elamin; Elhadi A. Ahmed; Bakri Y M. Nour; Sanaa E. Hussein

doi:10.53730/ijhs.v6nS1.7182

Authors

Albadawi A Talha
aaabdelbagi@ju.edu.sa
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Skaka, Saudi Arabia (KSA) and Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
Abozer Y Elderdery Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Skaka, Saudi Arabia (KSA)
Esraa A. Goda Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
Adam D A Salim Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
Lana M Elamin Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan and Clinical Laboratory Sciences, AL-Ghad International College for applied Medical Sciences, Dammam, Saudi Arabia
Elhadi A. Ahmed Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
Bakri Y M. Nour Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan
Sanaa E. Hussein Department of clinical laboratory Sciences, College of Applied Medical Sciences, Jouf University, Skaka, Saudi Arabia (KSA) and Faculty of Medical Laboratory Sciences, University of Gezira, Wad Medani, Sudan

Keywords:

Haematological parameters, Plasmodium vivax, Malaria, Parasite density, Gezira State, Sudan

Abstract

Background: Despite the great effort of the malaria control program in Sudan, Plasmodium vivax malaria has remained a major challenge recently, causing significant morbidity with a variety of haematological changes. Objective: This study aims to investigate the effect of Plasmodium vivax malaria and their density on some haematological parameters in patients admitted to Wad Medani teaching hospital in Gezira state, Sudan. Methods: Some haematological parameters of 160 participants, 80 infected with vivax malaria (47 male and 33 female) and 80 non-infected with malaria, who were admitted to Wad Medani teaching hospital in Gezira state, Sudan during high transmission season between August and November 2018, were evaluated for some haematological parameters. Results: The parameters (haemoglobin, haematocrit, counts of red blood cells, platelets, white blood cells, lymphocytes, monocytes and eosinophils) were significantly lower in infected patients than malaria negatives. The platelets and haemoglobin were inversely correlated to parasite density in positive cases. Conclusion: The exhibition of some haematological parameters changes was closely related to patients infected with vivax malaria versus non-infected, and these changes could be used as a diagnostic criterion for vivax malaria diagnosis in endemic regions.

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