The sensitivity and specificity testes for diagnosis of rheumatoid arthritis/ Jordan

https://doi.org/10.53730/ijhs.v8nS1.15174

Authors

  • Nawal S. Faris Department of Allied Medical Sciences, Middle East university
  • Mohammad M Hadieh Medicinal and Pharmaceutical Chemistry, Jordan University and Technology
  • Omar M Hadieh Medicinal and Pharmaceutical Chemistry, Jordan University and Technology

Keywords:

Rheumatoid arthritis, ANA, ACCP, ASO and CRP Laboratory Tests

Abstract

Background: Prognosis, treatment, and even early detection of rheumatoid arthritis may all be effectively tracked.  Serological tests may be used to validate clinically suspected preliminary diagnoses of rheumatic disorders, track the effectiveness of treatment, and predict the prognosis of autoimmune diseases. for CRP, anti-citrullinated peptide antibodies, anti-streptolysine O, acute phase proteins, rheumatoid factor, and CRP.  Aims of the study: focused on diagnostic designs that tested the sensitivity and specificity of diagnoses. such as ANA, ACCP, ASO, and CRP Laboratory Tests of Rheumatoid arthritis. Methods: ELIZA tests were used to refer 79 individuals to the Immunology department, specifically the rheumatic ward. Statistical test: Statically analysis: was carried out using ANOVA. Results:  Most patients with RA tested positive for anti-CCP. 86% of RA patients have positive test findings. According to ASO, there may be an increase in RF without an increase in ASO in some circumstances. This is because there may be additional health issues contributing to the auto immune disease. Other results may also indicate an increase in ASO and CRP without an increase in RF. Conclusions: We came to the conclusion that ACCP antibodies and CRP are the most sensitive and specific tests for the diagnosis of RA.

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References

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antibodies in rheumatoid and nonrheumatoid rheumatic disorders: experience with 1162 patients. J heumatol. 2014; 41:23952402. DOI: https://doi.org/10.3899/jrheum.131375

Published

19-09-2024

How to Cite

Faris, N. S., Hadieh, M. M., & Hadieh, O. M. (2024). The sensitivity and specificity testes for diagnosis of rheumatoid arthritis/ Jordan. International Journal of Health Sciences, 8(S1), 1265–1270. https://doi.org/10.53730/ijhs.v8nS1.15174

Issue

Section

Peer Review Articles