Relationship between toxoplasma IgG avidity levels and abortion risk
Keywords:
Abortus, IgG Avidity, Toxoplasma Gondii, ToxoplasmosisAbstract
Abortion is still a problem that receives special attention because based on data from the World Health Organization (WHO), abortion accounts for 15-50% of the causes of maternal death in the world. One of the risk factors for abortion is infection during pregnancy, including toxoplasmosis. The aim of this study was to analyze whether there was a relationship between toxoplasma IgG avidity levels and the risk of abortion. The research uses a literature review study to identify, analyze, and evaluate scientific papers through MDPI, PubMed, and ScienceDirect data sources. 60 articles were produced from the four data sources, there were 7 articles that passed the inclusion criteria which are summarized in the PRISMA diagram. The results in one article mentioned two abortions and the other article mentioned 17 abortions, both in first trimester pregnant women with low toxoplasma IgG avidity levels. Both articles show the results that women who have low toxoplasma IgG avidity levels experience more abortions in the early trimester than women who have medium or high toxoplasma IgG avidity levels. The conclusion of this study was that there was a relationship between toxoplasma IgG avidity levels and the risk of abortion.
Downloads
References
Abdallah, Kamel, Karima, Samir, Djamel, Rachid, & Khatima. (2019). Cross-Sectional Survey on Toxoplasma gondii Infection in Cattle, Sheep, and Goats in Algeria: Seroprevalence and Risk Factors. Veterinary Sciences, 6(3), 63. https://doi.org/10.3390/vetsci6030063
Al-Adhroey, A. H., Mehrass, A. A.-K. O., Al-Shammakh, A. A., Ali, A. D., Akabat, M. Y. M., & Al-Mekhlafi, H. M. (2019). Prevalence and predictors of Toxoplasma gondii infection in pregnant women from Dhamar, Yemen. BMC Infectious Diseases, 19(1), 1089. https://doi.org/10.1186/s12879-019-4718-4
Alsammani, M. A. (2013). Seroepidemiology of Toxoplasma Gondii Infection in Women with First Trimester Spontaneous Miscarriage in Qena Governorate, Egypt. JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH. https://doi.org/10.7860/JCDR/2013/6480.3780
Al-Yami, F. S., Dar, F. K., Yousef, A. I., Al-Qurouni, B. H., Al-Jamea, L. H., Rabaan, A. A., Quiambao, J. V., Arulanantham, Z. J., & Woodman, A. (2021). A pilot study on screening for gestational/congenital toxoplasmosis of pregnant women at delivery in the Eastern Province of Saudi Arabia. Saudi Pharmaceutical Journal, 29(4), 343–350. https://doi.org/10.1016/j.jsps.2021.03.009
Bieńkowski, C., Aniszewska, M., Kowalczyk, M., Popielska, J., Zawadka, K., Ołdakowska, A., & Pokorska-Śpiewak, M. (2022). Analysis of Preventable Risk Factors for Toxoplasma gondii Infection in Pregnant Women: Case-Control Study. Journal of Clinical Medicine, 11(4), 1105. https://doi.org/10.3390/jcm11041105
Briciu, V., Ionică, A. M., Flonta, M., Almaș, A., Muntean, M., Topan, A., Horvat, M., Ungureanu, L., & Lupșe, M. (2023). Toxoplasmosis Screening during Pregnancy in a Romanian Infectious Diseases Tertiary Center: Results of a 15 Years Follow-Up Program. Microorganisms, 11(9), 2189. https://doi.org/10.3390/microorganisms11092189
Fallahi, S., Rostami, A., Nourollahpour Shiadeh, M., Behniafar, H., & Paktinat, S. (2018). An updated literature review on maternal-fetal and reproductive disorders of Toxoplasma gondii infection. Journal of Gynecology Obstetrics and Human Reproduction, 47(3), 133–140. https://doi.org/10.1016/j.jogoh.2017.12.003
Grada, S., Mihu, A. G., Oatis, D. A., Susan, M., Lupu, M. A., & Olariu, T. R. (2024). Prevalence of Toxoplasma gondii IgG Antibodies and Associated Risk Factors in Psychiatric Patients from Western Romania: A Cross-Sectional Study. Microorganisms, 12(1), 172. https://doi.org/10.3390/microorganisms12010172
Khan, K., & Khan, W. (2018). Congenital toxoplasmosis: An overview of the neurological and ocular manifestations. Parasitology International, 67(6), 715–721. https://doi.org/10.1016/j.parint.2018.07.004
Kheirandish, F., Ezatpour, B., Fallahi, S., Tarahi, M. J., Hosseini, P., Karimi Rouzbahani, A., Seyyed Tabaei, S. J., & Akbari, S. (2019). Toxoplasma Serology Status and Risk of Miscarriage, A Case-Control Study among Women with A History of Spontaneous Abortion. International Journal of Fertility and Sterility, 13(3). https://doi.org/10.22074/ijfs.2019.5740
Machumi, I., M Mirambo, M., Ruganuza, D., Rambau, P., N Massinde, A., Kihunrwa, A., E Mshana, S., & Morona, D. (2017). Factors Associated With Toxoplasma gondii IgG and IgM Antibodies, and Placental Histopathological Changes Among Women With Spontaneous Abortion in Mwanza City, Tanzania. East African Health Research Journal, 1(2), 86–94. https://doi.org/10.24248/eahrj.v1i2.554
Meroni, V., Genco, F., Scudeller, L., Brenier-Pinchart, M.-P., Fricker-Hidalgo, H., L’Ollivier, C., Paris, L., & Pelloux, H. (2022). Diagnostic Accuracy of LDBIO-Toxo II IgG and IgM Western Blot in Suspected Seroconversion in Pregnancy: A Multicentre Study. Pathogens, 11(6), 665. https://doi.org/10.3390/pathogens11060665
Milne, G., Webster, J. P., & Walker, M. (2020). Toxoplasma gondii: An Underestimated Threat? Trends in Parasitology, 36(12), 959–969. https://doi.org/10.1016/j.pt.2020.08.005
Mocanu, A. G., Stoian, D. L., Craciunescu, E. L., Ciohat, I. M., Motofelea, A. C., Navolan, D. B., Vilibic-Cavlek, T., Stevanovic, V., Nemescu, D., Forga, M., Daniluc, R., Ioana, A.-M., & Craina, M. (2022). The Impact of Latent Toxoplasma gondii Infection on Spontaneous Abortion History and Pregnancy Outcomes: A Large-Scale Study. Microorganisms, 10(10), 1944. https://doi.org/10.3390/microorganisms10101944
Muthoharoh, B. L., Yuriah, S., Gustiani, R., Agustina, Y. R., Indrawati, I., & Mufdlilah, M. (2022). Efficacy of early initiation of breastfeeding (EIB) for preventing hypothermia in newborns. Journal of Health Technology Assessment in Midwifery, 5(2), 82–95. https://doi.org/10.31101/jhtam.2211
Radoi, C. L., Zlatian, O., Balasoiu, M., Giubelan, L., Stoian, A. C., Dragonu, L., Neacsu, A., & Iliescu, D. G. (2023). Seroprevalence of Infections with TORCH Agents in Romania: A Systematic Review. Microorganisms, 11(8), 2120. https://doi.org/10.3390/microorganisms11082120
Rostami, A., Riahi, S. M., Esfandyari, S., Habibpour, H., Mollalo, A., Mirzapour, A., Behniafar, H., MohammadiMoghadam, S., Azizi Kyvanani, N., Aghaei, S., Bazrafshan, N., & Ghazvini, S. (2021). Geo-climatic factors and prevalence of chronic toxoplasmosis in pregnant women: A meta-analysis and meta-regression. Environmental Pollution, 288, 117790. https://doi.org/10.1016/j.envpol.2021.117790
Siddiqui, N., Khan, H. M., Rabbani, T., Khan, P. A., & Shujatullah, F. (2015). Role of Toxplasma gondii serology in patients with habitual abortions. Asian Pacific Journal of Tropical Disease, 5(6), 471–473. https://doi.org/10.1016/S2222-1808(15)60818-0
Siddiqui, N., Shujatullah, F., Khan, H. M., Rabbani, T., & Khan, P. A. (2014). IgG Avidity Antibodies against Toxoplasma gondii in High Risk Females of Reproductive Age Group in India. The Korean Journal of Parasitology, 52(5), 487–491. https://doi.org/10.3347/kjp.2014.52.5.487
Silva-Díaz, H., Arriaga-Deza, E. V., Failoc-Rojas, V. E., Alarcón-Flores, Y. R., Rojas-Rojas, S. Y., Becerra-Gutiérrez, L. K., Mera-Villasis, K. M., Aguilar-Gamboa, F. R., & Silva-García, T. (2020). Seroprevalence of toxoplasmosis in pregnant women and its associated factors among hospital and community populations in Lambayeque, Peru. Revista Da Sociedade Brasileira de Medicina Tropical, 53, e20190164. https://doi.org/10.1590/0037-8682-0164-2019
Valladares-Garrido, M. J., Failoc-Rojas, V. E., Ichiro-Peralta, C., Astudillo-Rueda, D., & Silva-Díaz, H. (2022). Toxoplasma gondii Infection and Threatened Abortion in Women from Northern Peru. Infectious Diseases in Obstetrics and Gynecology, 2022, 1–7. https://doi.org/10.1155/2022/1163655
Vueba, A. N., Faria, C. P., Almendra, R., Santana, P., & Sousa, M. D. C. (2020). Serological prevalence of toxoplasmosis in pregnant women in Luanda (Angola): Geospatial distribution and its association with socio-demographic and clinical-obstetric determinants. PLOS ONE, 15(11), e0241908. https://doi.org/10.1371/journal.pone.0241908
Yuriah, S. (2024). Hubungan Tingkat Pengetahuan Ibu Hamil Tentang Hiv/Aids Dengan Sikap Terhadap Provider Initiated Test And Counselling (PITC). Jurnal Kesehatan Abdurahman Palembang, 13(1). https://doi.org/10.53730/ijhs.v7ns1.14631
Yuriah, S., Juniarti, S., & Sepriani, P. (2023). Midwifery care for Mrs “Y” at BPM Soraya Palembang. International Journal of Health Sciences, 7(S1), 2966–2984. https://doi.org/10.53730/ijhs.v7nS1.14631
Yuriah, S., & Kartini, F. (2022). Factors Affecting With The Prevalence Of Hypertension In Pregnancy: Scoping Review. PLACENTUM: Jurnal Ilmiah Kesehatan Dan Aplikasinya, 10(1), 1. https://doi.org/10.20961/placentum.v10i1.54822
Yuriah, S., Kartini, F., & Isnaeni, Y. (2022). Experiences of women with preeclampsia. International Journal of Health & Medical Sciences, 5(3), 201–210. https://doi.org/10.21744/ijhms.v5n3.1901
Zeinali, S., Khademvatan, S., Jafari, R., Vazifekhah, S., Yousefi, E., & Behroozi-Lak, T. (2023). Prevalence and risk factors of Toxoplasma gondii infection among women with miscarriage and their aborted fetuses in the northwest of Iran. PLOS ONE, 18(10), e0283493. https://doi.org/10.1371/journal.pone.0283493
Published
How to Cite
Issue
Section
Copyright (c) 2024 International journal of health sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Articles published in the International Journal of Health Sciences (IJHS) are available under Creative Commons Attribution Non-Commercial No Derivatives Licence (CC BY-NC-ND 4.0). Authors retain copyright in their work and grant IJHS right of first publication under CC BY-NC-ND 4.0. Users have the right to read, download, copy, distribute, print, search, or link to the full texts of articles in this journal, and to use them for any other lawful purpose.
Articles published in IJHS can be copied, communicated and shared in their published form for non-commercial purposes provided full attribution is given to the author and the journal. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgment of its initial publication in this journal.
This copyright notice applies to articles published in IJHS volumes 4 onwards. Please read about the copyright notices for previous volumes under Journal History.
